It is possible that the TCAB1-mediated “swap” is just not captured through the conformation characterized in the cryo-EM structure. Characterizing a greater fraction of your holoenzyme particles in the Lively chromatographic portion will likely lead to the identification of added conformational states. The cryo-EM characterization of human telomerase also reveals https://charlieu468lfv1.topbloghub.com/profile