Butabarbital will lower the level or outcome of fedratinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Effect of coadministering a strong CYP3A4 inducer with fedratinib has not been studied. butabarbital will minimize the level or result of pioglitazone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance U... https://malcolmf555jgb2.blazingblog.com/profile