CNS Depressants Coadministration of zolpidem with other CNS depressants improves the danger of CNS despair. Concomitant use of zolpidem with these medicines may possibly maximize drowsiness and psychomotor impairment, together with impaired driving ability [seeWarnings and Safety measures (5. I'm creating this thread as I am noticing a trend on https://margarete542nub8.wikievia.com/user